Sona Kang

Our research goal is to gain more accurate understanding of how epigenetic and transcriptional regulators control (patho)physiology of adipose and other metabolic tissues. Ultimately, we hope to identify novel drug targets for more safe and efficient therapeutic intervention to relevant metabolic disorders including obesity and type 2 diabetes. The key questions that we address are; 1) What are the core epigenetic events underlying obesity and insulin resistance, especially in the fat tissue? 2) Does the adverse epigenetic have a direct contribution to the pathogenesis?, 3) If so, how does so?, and, 4) Can we fix the adverse epigenetic events to mitigate the condition?