Joseph L. Napoli

The Napoli lab studies regulation of the metabolon that generates the autocoid all-trans-retinoic acid (atRA) from retinol (vitamin A), and the function of atRA in in modulating intermediary metabolism (energy balance), diabesity, adipogenesis, bone health (osteoporosis) and blood glucose control. We use a combination of analytical chemistry, bioimaging, biochemistry and molecular and cell biology to determine the physiological effects of atRA.